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Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium.
Hässler, Signe; Bachelet, Delphine; Duhaze, Julianne; Szely, Natacha; Gleizes, Aude; Hacein-Bey Abina, Salima; Aktas, Orhan; Auer, Michael; Avouac, Jerôme; Birchler, Mary; Bouhnik, Yoram; Brocq, Olivier; Buck-Martin, Dorothea; Cadiot, Guillaume; Carbonnel, Franck; Chowers, Yehuda; Comabella, Manuel; Derfuss, Tobias; De Vries, Niek; Donnellan, Naoimh; Doukani, Abiba; Guger, Michael; Hartung, Hans-Peter; Kubala Havrdova, Eva; Hemmer, Bernhard; Huizinga, Tom; Ingenhoven, Kathleen; Hyldgaard-Jensen, Poul Erik; Jury, Elizabeth C; Khalil, Michael; Kieseier, Bernd; Laurén, Anna; Lindberg, Raija; Loercher, Amy; Maggi, Enrico; Manson, Jessica; Mauri, Claudia; Mohand Oumoussa, Badreddine; Montalban, Xavier; Nachury, Maria; Nytrova, Petra; Richez, Christophe; Ryner, Malin; Sellebjerg, Finn; Sievers, Claudia; Sikkema, Dan; Soubrier, Martin; Tourdot, Sophie; Trang, Caroline; Vultaggio, Alessandra.
Affiliation
  • Hässler S; CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France.
  • Bachelet D; Sorbonne Université, INSERM UMR 959, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.
  • Duhaze J; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi), Paris, France.
  • Szely N; CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France.
  • Gleizes A; Department of Biostatistical Epidemiology and Clinical Research, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris AP-HP.Nord, INSERM CIC-EC 1425, Paris, France.
  • Hacein-Bey Abina S; CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France.
  • Aktas O; CHU Ste-Justine Research Center, Montreal, Canada.
  • Auer M; INSERM UMR 996, Faculty of Pharmacy, Paris-Sud University, Paris-Saclay University, Châtenay-Malabry, France.
  • Avouac J; INSERM UMR 996, Faculty of Pharmacy, Paris-Sud University, Paris-Saclay University, Châtenay-Malabry, France.
  • Birchler M; Clinical Immunology Laboratory, AP-HP, Le Kremlin-Bicêtre Hospital, Paris-Sud University Hospitals, Le Kremlin-Bicêtre, France.
  • Bouhnik Y; Clinical Immunology Laboratory, AP-HP, Le Kremlin-Bicêtre Hospital, Paris-Sud University Hospitals, Le Kremlin-Bicêtre, France.
  • Brocq O; UTCBS, CNRS UMR 8258, INSERM U1022, Faculty of Pharmacy, Paris-Descartes-Sorbonne-Cite University, Paris, France.
  • Buck-Martin D; University of Düsseldorf, Medical Faculty, Department of Neurology, Düsseldorf, Germany.
  • Cadiot G; Innsbruck Medical University, Department of Neurology, Innsbruck, Austria.
  • Carbonnel F; Paris University, Paris Descartes University, INSERM U1016, Paris, France.
  • Chowers Y; Rheumatology department, Cochin Hospital, AP-HP.CUP, Paris, France.
  • Comabella M; GlaxoSmithKline, Clinical Immunology-Biopharm, Collegeville, Pennsylvania, United States of America.
  • Derfuss T; AP-HP, Hôpital Beaujon, Paris, France.
  • De Vries N; GETAID, Paris, France.
  • Donnellan N; Princess Grace Hospital, Rheumatology, Monaco.
  • Doukani A; Department of Neurology, Technische Universität München, Munich, Germany.
  • Guger M; GETAID, Paris, France.
  • Hartung HP; Service d'hépato-gastroentérologie, University Hospital of Reims, Reims, France.
  • Kubala Havrdova E; GETAID, Paris, France.
  • Hemmer B; Department of Gastroenterology, AP-HP, Hôpital Kremlin-Bicêtre, France.
  • Huizinga T; Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel; Bruce Rappaport School of Medicine, Technion Israel Institute of Technology, Haifa, Israel; Clinical Research Institute, Rambam Health Care Campus, Haifa, Israel.
  • Ingenhoven K; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat). Institut de Recerca Vall d'Hebron (VHIR). Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Hyldgaard-Jensen PE; Departments of Biomedicine and Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
  • Jury EC; Rheumatology & Clinical Immunology, Amsterdam UMC | AMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Khalil M; Ipsen Biopharm Ltd, Berkshire, United Kingdom.
  • Kieseier B; Sorbonne Université, Inserm, UMS Production et Analyse des données en Sciences de la vie et en Santé, UMS 37 PASS, Plateforme Post-génomique de la Pitié-Salpêtrière, P3S, Paris, France.
  • Laurén A; Clinic for Neurology 2, Med Campus III, Kepler University Hospital GmbH, Linz, Austria.
  • Lindberg R; University of Düsseldorf, Medical Faculty, Department of Neurology, Düsseldorf, Germany.
  • Loercher A; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
  • Maggi E; Department of Neurology, Technische Universität München, Munich, Germany.
  • Manson J; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Mauri C; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Mohand Oumoussa B; University of Düsseldorf, Medical Faculty, Department of Neurology, Düsseldorf, Germany.
  • Montalban X; Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Nachury M; Centre for Rheumatology Research, University College London, London, United Kingdom.
  • Nytrova P; Department of Neurology, Medical University of Graz, Austria.
  • Richez C; University of Düsseldorf, Medical Faculty, Department of Neurology, Düsseldorf, Germany.
  • Ryner M; Svar Life Science, Malmö, Sweden.
  • Sellebjerg F; Departments of Biomedicine and Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
  • Sievers C; GlaxoSmithKline, Clinical Immunology-Biopharm, Collegeville, Pennsylvania, United States of America.
  • Sikkema D; Dipartimento di Medicina Sperimentale e Clínica, Università di Firenze, Firenze, Italy.
  • Soubrier M; Immunology Area of Bambino Gesù Pediatric Hospital, IRCCS, Rome, Italy.
  • Tourdot S; Department of Rheumatology, University College London Hospital, London, United Kingdom.
  • Trang C; Centre for Rheumatology Research, University College London, London, United Kingdom.
  • Vultaggio A; Sorbonne Université, Inserm, UMS Production et Analyse des données en Sciences de la vie et en Santé, UMS 37 PASS, Plateforme Post-génomique de la Pitié-Salpêtrière, P3S, Paris, France.
PLoS Med ; 17(10): e1003348, 2020 10.
Article in En | MEDLINE | ID: mdl-33125391
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Biological Products Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Journal subject: MEDICINA Year: 2020 Type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Biological Products Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Journal subject: MEDICINA Year: 2020 Type: Article Affiliation country: France