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Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells.
Baharom, Faezzah; Ramirez-Valdez, Ramiro A; Tobin, Kennedy K S; Yamane, Hidehiro; Dutertre, Charles-Antoine; Khalilnezhad, Ahad; Reynoso, Glennys V; Coble, Vincent L; Lynn, Geoffrey M; Mulè, Matthew P; Martins, Andrew J; Finnigan, John P; Zhang, Xiao Meng; Hamerman, Jessica A; Bhardwaj, Nina; Tsang, John S; Hickman, Heather D; Ginhoux, Florent; Ishizuka, Andrew S; Seder, Robert A.
Affiliation
  • Baharom F; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Ramirez-Valdez RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Tobin KKS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Yamane H; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Dutertre CA; Singapore Immunology Network, A*STAR, Singapore, Singapore.
  • Khalilnezhad A; Program in Emerging Infectious Disease, Duke-National University of Singapore Medical School, Singapore, Singapore.
  • Reynoso GV; Singhealth Translational Immunology and Inflammation Centre, Singapore, Singapore.
  • Coble VL; Singapore Immunology Network, A*STAR, Singapore, Singapore.
  • Lynn GM; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Mulè MP; Viral Immunity and Pathogenesis Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Martins AJ; Avidea Technologies, Baltimore, MD, USA.
  • Finnigan JP; Avidea Technologies, Baltimore, MD, USA.
  • Zhang XM; Systems Genomics and Bioinformatics Unit, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Hamerman JA; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Bhardwaj N; Systems Genomics and Bioinformatics Unit, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Tsang JS; Department of Medicine, Division of Hematology/Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY, USA.
  • Hickman HD; Singapore Immunology Network, A*STAR, Singapore, Singapore.
  • Ginhoux F; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
  • Ishizuka AS; Department of Medicine, Division of Hematology/Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY, USA.
  • Seder RA; Systems Genomics and Bioinformatics Unit, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Nat Immunol ; 22(1): 41-52, 2021 01.
Article in En | MEDLINE | ID: mdl-33139915
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Cancer Vaccines / Hepatocyte Nuclear Factor 1-alpha / Nanoparticles / Antigens, Neoplasm Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article Affiliation country: United States
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Cancer Vaccines / Hepatocyte Nuclear Factor 1-alpha / Nanoparticles / Antigens, Neoplasm Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Type: Article Affiliation country: United States