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ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity.
Liu, Lu; Inoki, Ayaka; Fan, Kelly; Mao, Fengbiao; Shi, Guojun; Jin, Xi; Zhao, Meiling; Ney, Gina; Jones, Morgan; Sun, Shengyi; Dou, Yali; Inoki, Ken; Qi, Ling; Li, Qing.
Affiliation
  • Liu L; Department of Internal Medicine.
  • Inoki A; Department of Internal Medicine.
  • Fan K; Department of Internal Medicine.
  • Mao F; Department of Pathology.
  • Shi G; Department of Molecular & Integrative Physiology, and.
  • Jin X; Department of Internal Medicine.
  • Zhao M; Department of Internal Medicine.
  • Ney G; Department of Pediatrics, University of Michigan, Ann Arbor, MI.
  • Jones M; Department of Internal Medicine.
  • Sun S; Center for Molecular Medicine and Genetics, Department of Microbiology, Immunology, and Biochemistry, Wayne State University School of Medicine, Detroit, MI; and.
  • Dou Y; Department of Pathology.
  • Inoki K; Department of Internal Medicine.
  • Qi L; Department of Molecular & Integrative Physiology, and.
  • Li Q; Department of Internal Medicine.
Blood ; 136(26): 2975-2986, 2020 12 24.
Article in En | MEDLINE | ID: mdl-33150381
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Cell Proliferation / Endoplasmic Reticulum / TOR Serine-Threonine Kinases / Endoplasmic Reticulum-Associated Degradation Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Blood Year: 2020 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Cell Proliferation / Endoplasmic Reticulum / TOR Serine-Threonine Kinases / Endoplasmic Reticulum-Associated Degradation Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Blood Year: 2020 Type: Article