Phenolic bisabolane and cuparene sesquiterpenoids with anti-inflammatory activities from the deep-sea-derived Aspergillus sydowii MCCC 3A00324 fungus.

Niu, Siwen; Yang, Longhe; Zhang, Gaiyun; Chen, Tingting; Hong, Bihong; Pei, Shengxiang; Shao, Zongze

Niu, Siwen; Yang, Longhe; Zhang, Gaiyun; Chen, Tingting; Hong, Bihong; Pei, Shengxiang; Shao, Zongze.

Affiliation

Niu S; Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China; Technology Innovation Center for Exploitation of Marine Biological Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen
Yang L; Technology Innovation Center for Exploitation of Marine Biological Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China.
Zhang G; Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China.
Chen T; Technology Innovation Center for Exploitation of Marine Biological Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China.
Hong B; Technology Innovation Center for Exploitation of Marine Biological Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China. Electronic address: bhhong@tio.org.cn.
Pei S; Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China.
Shao Z; Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, People's Republic of China. Electronic address: shaozongze@tio.org.cn.

Bioorg Chem ; 105: 104420, 2020 12.

Article in En | MEDLINE | ID: mdl-33152648

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Aspergillus/chemistry; Monocyclic Sesquiterpenes/pharmacology; Sesquiterpenes/pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Anti-Inflammatory Agents, Non-Steroidal/isolation & purification; Aspergillus/metabolism; Cells, Cultured; Dose-Response Relationship, Drug; Fermentation; Lipopolysaccharides/antagonists & inhibitors; Lipopolysaccharides/pharmacology; Mice; Molecular Structure; Monocyclic Sesquiterpenes/chemistry; Monocyclic Sesquiterpenes/isolation & purification; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Nitric Oxide/antagonists & inhibitors; Nitric Oxide/biosynthesis; Sesquiterpenes/chemistry; Sesquiterpenes/isolation & purification; Structure-Activity Relationship

Key words

Anti-inflammatory activities; Aspergillus sydowii; Bisabolanes; Deep-sea-derived fungus; Sesquiterpenoids

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus / Sesquiterpenes / Anti-Inflammatory Agents, Non-Steroidal / Monocyclic Sesquiterpenes Limits: Animals Language: En Journal: Bioorg Chem Year: 2020 Type: Article

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