Role of pre-transplant MRD level detected by flow cytometry in recipients of allogeneic stem cell transplantation with AML.

Klyuchnikov, Evgeny; Christopeit, Maximilian; Badbaran, Anita; Bacher, Ulrike; Fritzsche-Friedland, Ulrike; von Pein, Ute-Marie; Wolschke, Christine; Kröger, Nicolaus

Klyuchnikov, Evgeny; Christopeit, Maximilian; Badbaran, Anita; Bacher, Ulrike; Fritzsche-Friedland, Ulrike; von Pein, Ute-Marie; Wolschke, Christine; Kröger, Nicolaus.

Affiliation

Klyuchnikov E; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
Christopeit M; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
Badbaran A; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
Bacher U; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, Bern, Switzerland.
Fritzsche-Friedland U; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
von Pein UM; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
Wolschke C; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.
Kröger N; Department of Stem Cell Transplantation, University Medical Center Eppendorf, University of Hamburg, Hamburg, Germany.

Eur J Haematol ; 106(5): 606-615, 2021 May.

Article in En | MEDLINE | ID: mdl-33249666

Subject(s)

Flow Cytometry; Leukemia, Myeloid, Acute/diagnosis; Neoplasm, Residual/diagnosis; Preoperative Care; Adult; Aged; Aged, 80 and over; Bone Marrow/pathology; Bone Marrow Cells/pathology; Clinical Decision-Making; Disease Management; Female; Flow Cytometry/methods; Hematopoietic Stem Cell Transplantation/methods; Humans; Leukemia, Myeloid, Acute/therapy; Male; Middle Aged; Outcome Assessment, Health Care; Preoperative Care/methods; Transplantation, Homologous; Young Adult

Key words

acute myeloid leukemia (AML); allogeneic stem cell transplantation; minimal residual disease (MRD); multicolor flow cytometry (MFC); relapse

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Preoperative Care / Leukemia, Myeloid, Acute / Neoplasm, Residual / Flow Cytometry Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur J Haematol Journal subject: HEMATOLOGIA Year: 2021 Type: Article Affiliation country: Germany

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