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A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
Cui, Xiao-Long; Nie, Ji; Ku, Jeremy; Dougherty, Urszula; West-Szymanski, Diana C; Collin, Francois; Ellison, Christopher K; Sieh, Laura; Ning, Yuhong; Deng, Zifeng; Zhao, Carolyn W T; Bergamaschi, Anna; Pekow, Joel; Wei, Jiangbo; Beadell, Alana V; Zhang, Zhou; Sharma, Geeta; Talwar, Raman; Arensdorf, Patrick; Karpus, Jason; Goel, Ajay; Bissonnette, Marc; Zhang, Wei; Levy, Samuel; He, Chuan.
Affiliation
  • Cui XL; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Nie J; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Ku J; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Dougherty U; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • West-Szymanski DC; Bluestar Genomics Inc., San Diego, CA, USA.
  • Collin F; Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Ellison CK; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Sieh L; Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Ning Y; Bluestar Genomics Inc., San Diego, CA, USA.
  • Deng Z; Bluestar Genomics Inc., San Diego, CA, USA.
  • Zhao CWT; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Bergamaschi A; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Pekow J; Bluestar Genomics Inc., San Diego, CA, USA.
  • Wei J; Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Beadell AV; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Zhang Z; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Sharma G; Bluestar Genomics Inc., San Diego, CA, USA.
  • Talwar R; Department of Medicine, University of Chicago, Chicago, IL, USA.
  • Arensdorf P; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Karpus J; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Goel A; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.
  • Bissonnette M; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.
  • Zhang W; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Levy S; City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • He C; Bluestar Genomics Inc., San Diego, CA, USA.
Nat Commun ; 11(1): 6161, 2020 12 02.
Article in En | MEDLINE | ID: mdl-33268789
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / DNA / Genome, Human / Enhancer Elements, Genetic / Cytosine / 5-Methylcytosine / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / DNA / Genome, Human / Enhancer Elements, Genetic / Cytosine / 5-Methylcytosine / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: United States