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Pembrolizumab plus GX-188E therapeutic DNA vaccine in patients with HPV-16-positive or HPV-18-positive advanced cervical cancer: interim results of a single-arm, phase 2 trial.
Youn, Jin Won; Hur, Soo-Young; Woo, Jung Won; Kim, Yong-Man; Lim, Myong Cheol; Park, Sang Yoon; Seo, Sang Soo; No, Jae Hong; Kim, Byoung-Gie; Lee, Jae-Kwan; Shin, So Jin; Kim, Kyungun; Chaney, Marya F; Choi, Yoon-Jeong; Suh, You Suk; Park, Jong Sup; Sung, Young Chul.
Affiliation
  • Youn JW; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Hur SY; The Catholic University of Korea, Seoul St Mary's Hospital, Seocho-gu, Seoul, South Korea.
  • Woo JW; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Kim YM; Asan Medical Center, Songpa-gu, Seoul, South Korea.
  • Lim MC; National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, South Korea.
  • Park SY; National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, South Korea.
  • Seo SS; National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, South Korea.
  • No JH; Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Kim BG; Samsung Medical Center, Gangnam-gu, Seoul, South Korea.
  • Lee JK; Korea University Guro Hospital, Guro-gu, Seoul, South Korea.
  • Shin SJ; Keimyung University Dongsan Medical Center, Dalseo-gu, Daegu, South Korea.
  • Kim K; National Onco Venture, Ilsandong-gu, Goyang-si, Gyeonggi-do, South Korea.
  • Chaney MF; Merck & Co, Kenilworth, NJ, USA.
  • Choi YJ; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Suh YS; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Park JS; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Sung YC; Genexine, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea; Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea. Electronic address: ycsung@genexine.com.
Lancet Oncol ; 21(12): 1653-1660, 2020 12.
Article in En | MEDLINE | ID: mdl-33271094
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Vaccines, DNA / Papillomavirus Infections / Human papillomavirus 16 / Human papillomavirus 18 / Papillomavirus Vaccines / Antibodies, Monoclonal, Humanized / Antineoplastic Agents, Immunological Type of study: Clinical_trials / Diagnostic_studies / Observational_studies Limits: Adult / Female / Humans / Middle aged Country/Region as subject: Asia Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2020 Type: Article Affiliation country: South Korea
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Vaccines, DNA / Papillomavirus Infections / Human papillomavirus 16 / Human papillomavirus 18 / Papillomavirus Vaccines / Antibodies, Monoclonal, Humanized / Antineoplastic Agents, Immunological Type of study: Clinical_trials / Diagnostic_studies / Observational_studies Limits: Adult / Female / Humans / Middle aged Country/Region as subject: Asia Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2020 Type: Article Affiliation country: South Korea