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Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial.
Goldman, Jonathan W; Dvorkin, Mikhail; Chen, Yuanbin; Reinmuth, Niels; Hotta, Katsuyuki; Trukhin, Dmytro; Statsenko, Galina; Hochmair, Maximilian J; Özgüroglu, Mustafa; Ji, Jun Ho; Garassino, Marina Chiara; Voitko, Oleksandr; Poltoratskiy, Artem; Ponce, Santiago; Verderame, Francesco; Havel, Libor; Bondarenko, Igor; Kazarnowicz, Andrzej; Losonczy, György; Conev, Nikolay V; Armstrong, Jon; Byrne, Natalie; Thiyagarajah, Piruntha; Jiang, Haiyi; Paz-Ares, Luis.
Affiliation
  • Goldman JW; David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
  • Dvorkin M; BHI of Omsk Region Clinical Oncology Dispensary, Omsk, Russia.
  • Chen Y; Cancer and Hematology Centers of Western Michigan, Grand Rapids, MI, USA.
  • Reinmuth N; Asklepios Lung Clinic, Munich-Gauting, Germany.
  • Hotta K; Okayama University Hospital, Okayama, Japan.
  • Trukhin D; Odessa Regional Oncological Dispensary, Odessa, Ukraine.
  • Statsenko G; Omsk Regional Cancer Centre, Omsk, Russia.
  • Hochmair MJ; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna, Austria.
  • Özgüroglu M; Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey.
  • Ji JH; Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea.
  • Garassino MC; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Voitko O; Kyiv City Clinical Oncological Centre, Kiev, Ukraine.
  • Poltoratskiy A; Petrov Research Institute of Oncology, St Petersburg, Russia.
  • Ponce S; Department of Medical Oncology, Hospital Universitario 12 de Octubre, H120-CNIO Lung Cancer Unit, Universidad Complutense and Ciberonc, Madrid, Spain.
  • Verderame F; Azienda Ospedaliera Ospedali Riuniti PO Vincenzo Cervello, Palermo, Italy.
  • Havel L; Thomayer Hospital, First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Bondarenko I; Dnipropetrovsk Medical Academy, Dnipro, Ukraine.
  • Kazarnowicz A; Tuberculosis and Lung Disease Hospital, Olsztyn, Poland.
  • Losonczy G; Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Conev NV; Clinic of Medical Oncology, University Multiprofile Hospital for Active Treatment St Marina, Varna, Bulgaria.
  • Armstrong J; AstraZeneca, Cambridge, UK.
  • Byrne N; AstraZeneca, Cambridge, UK.
  • Thiyagarajah P; AstraZeneca, Cambridge, UK.
  • Jiang H; AstraZeneca, Gaithersburg, MD, USA.
  • Paz-Ares L; Department of Medical Oncology, Hospital Universitario 12 de Octubre, H120-CNIO Lung Cancer Unit, Universidad Complutense and Ciberonc, Madrid, Spain. Electronic address: lpazaresr@seom.org.
Lancet Oncol ; 22(1): 51-65, 2021 01.
Article in En | MEDLINE | ID: mdl-33285097
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Carboplatin / Cisplatin / Etoposide / Small Cell Lung Carcinoma / Antibodies, Monoclonal, Humanized / Lung Neoplasms / Antibodies, Monoclonal Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Carboplatin / Cisplatin / Etoposide / Small Cell Lung Carcinoma / Antibodies, Monoclonal, Humanized / Lung Neoplasms / Antibodies, Monoclonal Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2021 Type: Article Affiliation country: United States