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Adult form of Langerhans cell histiocytosis with pulmonary and hepatic involvement mimicking malignancy in a patient with chronic hepatitis C infection.
Moullet, Barbara; Kolev, Mirjam; Ebner, Lukas; Langer, Rupert; Gräni, Christoph; Obmann, Verena; Maurer, Martin; Semmo, Nasser; Christe, Andreas; Huber, Adrian Thomas.
Affiliation
  • Moullet B; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
  • Kolev M; Hepatology, Department of Visceral Surgery and Medicine, Inselspital University Hospital, University of Bern, Bern, Switzerland.
  • Ebner L; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
  • Langer R; Department of Pathology, Inselspital University Hospital, University of Bern, Bern, Switzerland.
  • Gräni C; Department of Cardiology, Inselspital University Hospital, University of Bern, Bern, Switzerland.
  • Obmann V; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
  • Maurer M; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
  • Semmo N; Hepatology, Department of Visceral Surgery and Medicine, Inselspital University Hospital, University of Bern, Bern, Switzerland.
  • Christe A; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
  • Huber AT; Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital University Hospital, University of Bern, Freiburgstrasse 10, Inselspital, 3010, Bern, Switzerland.
Radiol Case Rep ; 16(2): 327-333, 2021 Feb.
Article in En | MEDLINE | ID: mdl-33318775
Langerhans cell histiocytosis (LCH) is a myeloid neoplasm with inflammatory properties. There are few published reports of adult LCH with liver involvement, which is still poorly understood, but shows high morbidity and mortality. We report a case of a 37-year-old woman suffering from hepatitis C showing a LCH affecting the lung as well as the liver. Consistent with histology, we found an early stage of a proliferative/granulomatous phase of hepatobiliary LCH, whereas pulmonary findings showed a nodular stage of adult pulmonary LCH. Although hepatocellular carcinoma is a common malignancy in patients suffering from hepatitis C, it is crucial to keep in mind differential diagnosis for newly appearing liver lesions.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Radiol Case Rep Year: 2021 Type: Article Affiliation country: Switzerland
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Radiol Case Rep Year: 2021 Type: Article Affiliation country: Switzerland