Ligand Induced Cu<sup>II</sup> Transport Restricts Cancer and Mycobacterial Growth: Towards a Plug-and-Select Ion Channel Scaffold.

Saha, Parichita; Kumari Agarwala, Prema; Dadhich, Ruchika; Adhyapak, Pranav; Kapoor, Shobhna; Madhavan, Nandita

Ligand Induced Cu^II Transport Restricts Cancer and Mycobacterial Growth: Towards a Plug-and-Select Ion Channel Scaffold.

Saha, Parichita; Kumari Agarwala, Prema; Dadhich, Ruchika; Adhyapak, Pranav; Kapoor, Shobhna; Madhavan, Nandita.

Affiliation

Saha P; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
Kumari Agarwala P; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
Dadhich R; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
Adhyapak P; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
Kapoor S; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
Madhavan N; Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Chembiochem ; 22(8): 1424-1429, 2021 04 16.

Article in En | MEDLINE | ID: mdl-33347676

Subject(s)

Copper/metabolism; Ion Channels/antagonists & inhibitors; Mycobacterium/drug effects; Neoplasms/drug therapy; Oligopeptides/pharmacology; Cell Death/drug effects; Copper/chemistry; Humans; Ion Channels/metabolism; Ligands; Molecular Structure; Mycobacterium/growth & development; Neoplasms/metabolism; Neoplasms/pathology; Oligopeptides/chemistry

Key words

cell death; copper transport; ion channels; ion selectivity; peptides

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Copper / Ion Channels / Mycobacterium / Neoplasms Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2021 Type: Article Affiliation country: India

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