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A cell-based drug delivery platform for treating central nervous system inflammation.
Levy, Oren; Rothhammer, Veit; Mascanfroni, Ivan; Tong, Zhixiang; Kuai, Rui; De Biasio, Michael; Wang, Qingping; Majid, Tahir; Perrault, Christelle; Yeste, Ada; Kenison, Jessica E; Safaee, Helia; Musabeyezu, Juliet; Heinelt, Martina; Milton, Yuka; Kuang, Heidi; Lan, Haoyue; Siders, William; Multon, Marie-Christine; Rothblatt, Jonathan; Massadeh, Salam; Alaamery, Manal; Alhasan, Ali H; Quintana, Francisco J; Karp, Jeffrey M.
Affiliation
  • Levy O; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Rothhammer V; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Mascanfroni I; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Tong Z; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Kuai R; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • De Biasio M; Centre of Excellence for Biomedicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Wang Q; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Majid T; Department of Drug Metabolism and Pharmacokinetics, Sanofi R&D, Waltham, MA, USA.
  • Perrault C; Global Research Program and Portfolio Management, Sanofi-Genzyme, Cambridge, MA, USA.
  • Yeste A; Sanofi R&D, In Vitro Pharmacology, Integrated Drug Discovery, Centre de Recherche Vitry-Alfortville, Vitry-Sur-Seine, France.
  • Kenison JE; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Safaee H; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Musabeyezu J; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Heinelt M; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Milton Y; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Kuang H; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Lan H; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Siders W; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA.
  • Multon MC; Genzyme R&D, Neuroimmunology Research, Framingham, MA, USA.
  • Rothblatt J; Sanofi R&D, Translational Sciences, Centre de Recherche Vitry-Alfortville, Vitry-Sur-Seine, France.
  • Massadeh S; Sanofi R&D, Biologics Research, Cambridge, MA, 02139, USA.
  • Alaamery M; Developmental Medicine Department, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
  • Alhasan AH; Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
  • Quintana FJ; Developmental Medicine Department, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
  • Karp JM; Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
J Mol Med (Berl) ; 99(5): 663-671, 2021 05.
Article in En | MEDLINE | ID: mdl-33398468
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Heterologous / Drug Delivery Systems / Encephalomyelitis, Autoimmune, Experimental / Enzyme Inhibitors / Mesenchymal Stem Cells / Indoles / Maleimides / Multiple Sclerosis Limits: Animals / Female / Humans Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Type: Article Affiliation country: United States
Fulltext
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Heterologous / Drug Delivery Systems / Encephalomyelitis, Autoimmune, Experimental / Enzyme Inhibitors / Mesenchymal Stem Cells / Indoles / Maleimides / Multiple Sclerosis Limits: Animals / Female / Humans Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Type: Article Affiliation country: United States