Long noncoding RNA CRNDE functions as a diagnostic and prognostic biomarker in osteosarcoma, as well as promotes its progression via inhibition of miR-335-3p.

Yu, Yali; Wang, Leiming; Li, Zijun; Zheng, Yan; Shi, Zhisong; Wang, Guanghui

Long noncoding RNA CRNDE functions as a diagnostic and prognostic biomarker in osteosarcoma, as well as promotes its progression via inhibition of miR-335-3p.

Yu, Yali; Wang, Leiming; Li, Zijun; Zheng, Yan; Shi, Zhisong; Wang, Guanghui.

Affiliation

Wang L; Department of Laboratory, Zhengzhou Orthopedic Hospital, Zhengzhou, China.
Li Z; Department of Laboratory, Zhengzhou Orthopedic Hospital, Zhengzhou, China.
Zheng Y; Department of Laboratory, Zhengzhou Orthopedic Hospital, Zhengzhou, China.
Shi Z; Department of Orthopedic Surgery, Zhumadian Central Hospital, Zhumadian, China.
Wang G; Department of Orthopedic Surgery, Zhumadian Central Hospital, Zhumadian, China.

J Biochem Mol Toxicol ; 35(5): e22734, 2021 May.

Article in En | MEDLINE | ID: mdl-33522065

Subject(s)

Biomarkers, Tumor/metabolism; Bone Neoplasms/metabolism; MicroRNAs/metabolism; Osteosarcoma/metabolism; RNA, Long Noncoding/metabolism; RNA, Neoplasm/metabolism; Biomarkers, Tumor/genetics; Bone Neoplasms/diagnosis; Bone Neoplasms/genetics; Cell Line, Tumor; Humans; MicroRNAs/genetics; Osteosarcoma/diagnosis; Osteosarcoma/genetics; Prognosis; RNA, Long Noncoding/genetics; RNA, Neoplasm/genetics

Key words

OS; lncRNA CRNDE; miR-335-3p; migration; proliferation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / RNA, Neoplasm / Biomarkers, Tumor / Osteosarcoma / MicroRNAs / RNA, Long Noncoding Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Biochem Mol Toxicol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Year: 2021 Type: Article

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