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Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial.
Politch, Joseph A; Cu-Uvin, Susan; Moench, Thomas R; Tashima, Karen T; Marathe, Jai G; Guthrie, Kate M; Cabral, Howard; Nyhuis, Tara; Brennan, Miles; Zeitlin, Larry; Spiegel, Hans M L; Mayer, Kenneth H; Whaley, Kevin J; Anderson, Deborah J.
Affiliation
  • Politch JA; Boston University School of Medicine, Department of Medicine, Boston, Massachusetts, United States of America.
  • Cu-Uvin S; Alpert Medical School of Brown University, Department of Obstetrics and Gynecology and Medicine, Providence, Rhode Island, United States of America.
  • Moench TR; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
  • Tashima KT; Division of Infectious Diseases, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
  • Marathe JG; Boston University School of Medicine, Department of Medicine, Boston, Massachusetts, United States of America.
  • Guthrie KM; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
  • Cabral H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
  • Nyhuis T; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
  • Brennan M; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
  • Zeitlin L; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
  • Spiegel HML; Kelly Government Solutions, Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America.
  • Mayer KH; Harvard Medical School, Department of Medicine, Boston, Massachusetts, United States of America.
  • Whaley KJ; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
  • Anderson DJ; Boston University School of Medicine, Department of Medicine, Boston, Massachusetts, United States of America.
PLoS Med ; 18(2): e1003495, 2021 02.
Article in En | MEDLINE | ID: mdl-33534791

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Antibodies, Monoclonal Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Journal subject: MEDICINA Year: 2021 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Antibodies, Monoclonal Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: PLoS Med Journal subject: MEDICINA Year: 2021 Type: Article Affiliation country: United States