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Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial: Protocol and statistical analysis plan.
Munch, M W; Granholm, Anders; Myatra, S N; Vijayaraghavan, Bkt; Cronhjort, Maria; Wahlin, R R; Jakob, Stephan M; Cioccari, Luca; Kjaer, M N; Vesterlund, G K; Meyhoff, T S; Helleberg, Marie; Møller, M H; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; Kristiansen, K T; Ulrik, C S; Jørgensen, V L; Smitt, Margit; Bestle, Morten H; Andreasen, A S; Poulsen, L M; Rasmussen, B S; Brøchner, A C; Strøm, Thomas; Møller, Anders; Khan, M S; Padmanaban, Ajay; Divatia, J V; Saseedharan, Sanjith; Borawake, Kapil; Kapadia, Farhad; Dixit, Subhal; Chawla, Rajesh; Shukla, Urvi; Amin, Pravin; Chew, Michelle S; Gluud, Christian; Lange, Theis; Perner, Anders.
Affiliation
  • Munch MW; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Granholm A; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Myatra SN; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Vijayaraghavan B; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Cronhjort M; Department of Anaesthesia, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
  • Wahlin RR; Department of Critical Care, Apollo Hospitals, Chennai, India.
  • Jakob SM; Chennai Critical Care Consultants, Chennai, India.
  • Cioccari L; The George Institute for Global Health, University of New South Wales, New Delhi, India.
  • Kjaer MN; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
  • Vesterlund GK; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
  • Meyhoff TS; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Helleberg M; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Møller MH; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Benfield T; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Venkatesh B; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Hammond N; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Micallef S; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Bassi A; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • John O; Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Jha V; Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Kristiansen KT; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Ulrik CS; Department of Infectious Diseases, Center of Research & Disruption of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark.
  • Jørgensen VL; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Smitt M; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Bestle MH; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Andreasen AS; The George Institute for Global Health, University of New South Wales, New Delhi, India.
  • Poulsen LM; The George Institute for Global Health, University of New South Wales, New Delhi, India.
  • Rasmussen BS; Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
  • Brøchner AC; The George Institute for Global Health, University of New South Wales, New Delhi, India.
  • Strøm T; Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
  • Møller A; School of Public Health, Imperial College London, London, UK.
  • Khan MS; Department of Anaesthesia and Intensive Care, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Padmanaban A; Department of Respiratory Medicine, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Divatia JV; Department of Thoracic Anaesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Saseedharan S; Department of Neuroanaesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Borawake K; Department of Anaesthesiology and Intensive Care, Copenhagen University Hospital, Nordsjaelland, Denmark.
  • Kapadia F; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Dixit S; Department of Anaesthesia and Intensive Care, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Chawla R; Department of Anaesthesiology, Zealand University Hospital, Copenhagen, Denmark.
  • Shukla U; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
  • Amin P; Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
  • Chew MS; Department of Anaesthesia and Intensive Care, Kolding Hospital, Kolding, Denmark.
  • Gluud C; Department of Anaesthesia and Critical Care Medicine, Odense University Hospital, Odense C, Denmark.
  • Lange T; Department of Anaesthesia and Critical Care Medicine, Hospital Sønderjylland, University Hospital of Southern Denmark, Odense, Denmark.
  • Perner A; Department of Anaesthesia and Intensive Care, Naestved-Slagelse-Ringsted Hospital, Slagelse, Denmark.
Acta Anaesthesiol Scand ; 65(6): 834-845, 2021 Jul.
Article in En | MEDLINE | ID: mdl-33583034
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dexamethasone / Randomized Controlled Trials as Topic / Pandemics / SARS-CoV-2 / COVID-19 Drug Treatment / Anti-Inflammatory Agents Type of study: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Limits: Humans Country/Region as subject: Asia / Europa Language: En Journal: Acta Anaesthesiol Scand Year: 2021 Type: Article Affiliation country: Denmark
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dexamethasone / Randomized Controlled Trials as Topic / Pandemics / SARS-CoV-2 / COVID-19 Drug Treatment / Anti-Inflammatory Agents Type of study: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Limits: Humans Country/Region as subject: Asia / Europa Language: En Journal: Acta Anaesthesiol Scand Year: 2021 Type: Article Affiliation country: Denmark