Bioinformatic Analysis of the Wound Peptidome Reveals Potential Biomarkers and Antimicrobial Peptides.

Hartman, Erik; Wallblom, Karl; van der Plas, Mariena J A; Petrlova, Jitka; Cai, Jun; Saleh, Karim; Kjellström, Sven; Schmidtchen, Artur

Hartman, Erik; Wallblom, Karl; van der Plas, Mariena J A; Petrlova, Jitka; Cai, Jun; Saleh, Karim; Kjellström, Sven; Schmidtchen, Artur.

Affiliation

Hartman E; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Wallblom K; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
van der Plas MJA; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Petrlova J; LEO Foundation Center for Cutaneous Drug Delivery, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Cai J; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Saleh K; LEO Foundation Center for Cutaneous Drug Delivery, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Kjellström S; Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Schmidtchen A; Dermatology, Skane University Hospital, Lund, Sweden.

Front Immunol ; 11: 620707, 2020.

Article in En | MEDLINE | ID: mdl-33613550

Subject(s)

Biomarkers/analysis; Body Fluids/chemistry; Computational Biology/methods; Pore Forming Cytotoxic Proteins/analysis; Proteome/analysis; Wounds and Injuries/metabolism; Algorithms; Amino Acid Sequence; Chromatography, Liquid; Computer Simulation; Drainage; Face/surgery; Female; Hemoglobins/chemistry; Humans; Mastectomy; Neural Networks, Computer; Peptide Fragments/analysis; Plasma; Proteome/isolation & purification; Sequence Alignment; Skin Transplantation; Staphylococcal Infections/metabolism; Surgical Wound Infection/metabolism; Tandem Mass Spectrometry

Key words

antimicrobial peptide; bioinformatics; biomarkers; hemoglobin; mass spectrometry; peptidomics; wound healing; wound infection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wounds and Injuries / Body Fluids / Biomarkers / Computational Biology / Proteome / Pore Forming Cytotoxic Proteins Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Front Immunol Year: 2020 Type: Article Affiliation country: Sweden

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