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Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.
Vergara, Ismael A; Mintoff, Christopher P; Sandhu, Shahneen; McIntosh, Lachlan; Young, Richard J; Wong, Stephen Q; Colebatch, Andrew; Cameron, Daniel L; Kwon, Julia Lai; Wolfe, Rory; Peng, Angela; Ellul, Jason; Dou, Xuelin; Fedele, Clare; Boyle, Samantha; Arnau, Gisela Mir; Raleigh, Jeanette; Hatzimihalis, Athena; Szeto, Pacman; Mooi, Jennifer; Widmer, Daniel S; Cheng, Phil F; Amann, Valerie; Dummer, Reinhard; Hayward, Nicholas; Wilmott, James; Scolyer, Richard A; Cho, Raymond J; Bowtell, David; Thorne, Heather; Alsop, Kathryn; Cordner, Stephen; Woodford, Noel; Leditschke, Jodie; O'Brien, Patricia; Dawson, Sarah-Jane; McArthur, Grant A; Mann, Graham J; Levesque, Mitchell P; Papenfuss, Anthony T; Shackleton, Mark.
Affiliation
  • Vergara IA; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
  • Mintoff CP; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Sandhu S; Melanoma Institute of Australia, Sydney, Australia.
  • McIntosh L; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Young RJ; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Wong SQ; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
  • Colebatch A; Department of Mathematics and Statistics, The University of Melbourne, Parkville, VIC, Australia.
  • Cameron DL; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Kwon JL; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Wolfe R; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Peng A; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
  • Ellul J; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Dou X; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Fedele C; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
  • Boyle S; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Arnau GM; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
  • Raleigh J; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Hatzimihalis A; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Szeto P; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Mooi J; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Widmer DS; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Cheng PF; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Amann V; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Dummer R; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Hayward N; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
  • Wilmott J; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Scolyer RA; Department of Dermatology, University of Zürich Hospital, Zürich, Switzerland.
  • Cho RJ; Department of Dermatology, University of Zürich Hospital, Zürich, Switzerland.
  • Bowtell D; Department of Dermatology, University of Zürich Hospital, Zürich, Switzerland.
  • Thorne H; Department of Dermatology, University of Zürich Hospital, Zürich, Switzerland.
  • Alsop K; Melanoma Institute of Australia, Sydney, Australia.
  • Cordner S; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Woodford N; Melanoma Institute of Australia, Sydney, Australia.
  • Leditschke J; Melanoma Institute of Australia, Sydney, Australia.
  • O'Brien P; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia.
  • Dawson SJ; Sydney Medical School, The University of Sydney, Sydney, Australia.
  • McArthur GA; Department of Dermatology, University of California, San Francisco, CA, USA.
  • Mann GJ; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Levesque MP; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
  • Papenfuss AT; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Shackleton M; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Nat Commun ; 12(1): 1434, 2021 03 04.
Article in En | MEDLINE | ID: mdl-33664264
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Genome, Human / DNA Copy Number Variations / Aneuploidy / Melanoma Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: Australia
Fulltext
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XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Genome, Human / DNA Copy Number Variations / Aneuploidy / Melanoma Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: Australia