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Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair.
Rotolo, Jimmy A; Fong, Chii Shyang; Bodo, Sahra; Nagesh, Prashanth Kb; Fuller, John; Sharma, Thivashnee; Piersigilli, Alessandra; Zhang, Zhigang; Fuks, Zvi; Singh, Vijay K; Kolesnick, Richard.
Affiliation
  • Rotolo JA; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Fong CS; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Bodo S; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Nagesh PK; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Fuller J; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Sharma T; Laboratory of Signal Transduction, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Piersigilli A; Laboratory of Comparative Pathology, Rockefeller University, Weill Cornell Medicine and Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Zhang Z; Department of Epidemiology and Biostatistics and.
  • Fuks Z; Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Singh VK; Champalimaud Centre for the Unknown, Lisbon, Portugal.
  • Kolesnick R; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, and.
JCI Insight ; 6(8)2021 04 22.
Article in En | MEDLINE | ID: mdl-33724956
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ceramides / Acute Radiation Syndrome / Single-Chain Antibodies / Gastrointestinal Diseases / Intestine, Small Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ceramides / Acute Radiation Syndrome / Single-Chain Antibodies / Gastrointestinal Diseases / Intestine, Small Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2021 Type: Article Affiliation country: United States