Clinical pharmacology of oral and i.v. N-methylformamide: a pharmacologic basis for lack of clinical antineoplastic activity.

Rowinsky, E K; Noe, D A; Orr, D W; Grochow, L B; Ettinger, D S; Donehower, R C

Rowinsky, E K; Noe, D A; Orr, D W; Grochow, L B; Ettinger, D S; Donehower, R C.

Affiliation

Rowinsky EK; Johns Hopkins Oncology Center, Baltimore, Maryland 21205.

J Natl Cancer Inst ; 80(9): 671-8, 1988 Jul 06.

Article in En | MEDLINE | ID: mdl-3373556

Subject(s)

Antineoplastic Agents/pharmacokinetics; Formamides/pharmacokinetics; Administration, Oral; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/adverse effects; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Evaluation; Formamides/administration & dosage; Formamides/adverse effects; Formamides/pharmacology; Humans; Infusions, Intravenous; Nausea/chemically induced

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Collection: 01-internacional Database: MEDLINE Main subject: Formamides / Antineoplastic Agents Limits: Humans Language: En Journal: J Natl Cancer Inst Year: 1988 Type: Article

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