Chemogenetics drives paradigm change in the investigation of behavioral circuits and neural mechanisms underlying drug action.

Ozawa, Akihiko; Arakawa, Hiroyuki

Ozawa, Akihiko; Arakawa, Hiroyuki.

Affiliation

Ozawa A; Department of Biomedical Science, Florida Atlantic University, Boca Raton, FL, USA.
Arakawa H; Department of Psychology, Tokiwa University, Mito, Ibaraki, Japan; Department of Systems Physiology, University of Ryukyus, Faculty of Medicine, Nakagami District, Okinawa, Japan. Electronic address: harakawa@med.u-ryukyu.ac.jp.

Behav Brain Res ; 406: 113234, 2021 05 21.

Article in En | MEDLINE | ID: mdl-33741409

Subject(s)

Behavior, Animal/drug effects; Genetic Techniques; Genetic Vectors; Ligand-Gated Ion Channels; Neurotransmitter Agents; Pharmacogenetics; Psychopharmacology; Receptors, G-Protein-Coupled; Animals; Disease Models, Animal; Drug Design; Mice; Molecular Targeted Therapy; Protein Engineering

Key words

Animal models; Behavioral pharmacology; Chemogenetics; DREADDs; Drug treatment; Neural circuits; Research strategies

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmacogenetics / Psychopharmacology / Behavior, Animal / Genetic Techniques / Neurotransmitter Agents / Receptors, G-Protein-Coupled / Ligand-Gated Ion Channels / Genetic Vectors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Behav Brain Res Year: 2021 Type: Article Affiliation country: United States

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