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Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress.
Zhang, Wuchang; Liu, Wei; Jia, Lingfei; Chen, Demeng; Chang, Insoon; Lake, Michael; Bentolila, Laurent A; Wang, Cun-Yu.
Affiliation
  • Zhang W; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Liu W; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Jia L; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Chen D; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Chang I; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Lake M; Advanced Light Microscopy and Spectroscopy Laboratory, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Bentolila LA; Advanced Light Microscopy and Spectroscopy Laboratory, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Wang CY; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Bioengineering, Henr
Mol Cell ; 81(10): 2148-2165.e9, 2021 05 20.
Article in En | MEDLINE | ID: mdl-33743195
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Carcinoma, Squamous Cell / Epigenesis, Genetic / DNA Replication / Histone Demethylases / Jumonji Domain-Containing Histone Demethylases / Immunity Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Carcinoma, Squamous Cell / Epigenesis, Genetic / DNA Replication / Histone Demethylases / Jumonji Domain-Containing Histone Demethylases / Immunity Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States