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Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic.
Saunte, D M L; Pereiro-Ferreirós, M; Rodríguez-Cerdeira, C; Sergeev, A Y; Arabatzis, M; Prohic, A; Piraccini, B M; Lecerf, P; Nenoff, P; Kotrekhova, L P; Bosshard, P P; Padovese, V; Szepietowski, J C; Sigurgeirsson, B; Nowicki, R J; Schmid-Grendelmeier, P; Hay, R J.
Affiliation
  • Saunte DML; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Pereiro-Ferreirós M; Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
  • Rodríguez-Cerdeira C; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sergeev AY; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Arabatzis M; Dermatología, Faculty of Medicine, University of Santiago de Compostela, A Coruña, Spain.
  • Prohic A; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Piraccini BM; Department of Dermatology, Meixoeiro Hospital and University of Vigo, Vigo, Spain.
  • Lecerf P; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Nenoff P; Department of Clinical Immunology, Sechenov University, Moscow, Russia.
  • Kotrekhova LP; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Bosshard PP; Department of Dermatology, Medical School, Aristotle University, Thessaloniki, Greece.
  • Padovese V; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Szepietowski JC; Department of Dermatovenereology, University Sarajevo School of Science and Technology, Sarajevo Medical School, Sarajevo, Bosnia and Herzegovina.
  • Sigurgeirsson B; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Nowicki RJ; Dermatology -IRCCS Policlinico di Sant'Orsola Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy.
  • Schmid-Grendelmeier P; European Academy of Dermatology and Venereology TASK force on Mycology.
  • Hay RJ; Department of Dermatology, University Hospital Brugmann & Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
J Eur Acad Dermatol Venereol ; 35(7): 1582-1586, 2021 Jul.
Article in En | MEDLINE | ID: mdl-33768571
ABSTRACT

BACKGROUND:

Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.

OBJECTIVES:

To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.

METHODS:

A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.

RESULTS:

Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.

CONCLUSIONS:

This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tinea / Antifungal Agents Limits: Humans Country/Region as subject: Europa Language: En Journal: J Eur Acad Dermatol Venereol Journal subject: DERMATOLOGIA / DOENCAS SEXUALMENTE TRANSMISSIVEIS Year: 2021 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tinea / Antifungal Agents Limits: Humans Country/Region as subject: Europa Language: En Journal: J Eur Acad Dermatol Venereol Journal subject: DERMATOLOGIA / DOENCAS SEXUALMENTE TRANSMISSIVEIS Year: 2021 Type: Article