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Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFß1/MAPK signaling pathway.
Wu, Hui-Hui; Meng, Ting-Ting; Chen, Jia-Min; Meng, Fan-Liang; Wang, Shu-Ya; Liu, Rong-Han; Chen, Jia-Nan; Ning, Bin; Li, Ying; Su, Guo-Hai.
Affiliation
  • Wu HH; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
  • Meng TT; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
  • Chen JM; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
  • Meng FL; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
  • Wang SY; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
  • Liu RH; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
  • Chen JN; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
  • Ning B; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
  • Li Y; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
  • Su GH; Research Center for Translational Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China; Research Center for Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, China. Electronic address: sgh1630@zxyy.cn.
Biochem Biophys Res Commun ; 553: 172-179, 2021 05 14.
Article in En | MEDLINE | ID: mdl-33773140
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin II / Reactive Oxygen Species / MAP Kinase Signaling System / Dibenzocycloheptenes / Transforming Growth Factor beta1 / Fibroblasts Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin II / Reactive Oxygen Species / MAP Kinase Signaling System / Dibenzocycloheptenes / Transforming Growth Factor beta1 / Fibroblasts Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2021 Type: Article Affiliation country: China