Effect of propolis mouth rinse on oral microorganisms - a randomized controlled trial.
Clin Oral Investig
; 25(11): 6139-6146, 2021 Nov.
Article
in En
| MEDLINE
| ID: mdl-33786648
ABSTRACT
OBJECTIVES:
To evaluate and compare the efficacy of prepared propolis mouth rinse with Chlorhexidine mouthwash on oral pathogens and also the plaque and gingival index scores. MATERIAL ANDMETHODS:
A triple-blind, concurrent parallel randomized controlled trial was conducted on 120 participants randomized to 4 mouth rinse study groups (1) Hot Ethanolic Propolis extract; (2) Cold Ethanolic Propolis extract; (3) Chlorhexidine and (4) Distilled water. After a washout period of two weeks, oral prophylaxis and polishing was performed. Participants rinsed twice a day for 3 months. Saliva was collected at baseline, 5 min and 1 h for microbiological analysis. Plaque and Gingival index were recorded at baseline, 15 days, 1 month and 3 months. Repeated measures ANOVA with Bonferroni post hoc tests were used for statistical analysis.RESULTS:
A decline in the concentration of S. mutans was observed in samples collected after the use of mouth rinse (p < 0.05). In comparison with baseline, L. acidophilus and S. mutans count decreased simultaneously when exposed to Hot Ethanolic mouthwash group (5.5 × 102) and Chlorhexidine mouthwash (5.8 × 102) respectively. At the end of 3 months, similar reduction in plaque scores was found in Chlorhexidine (0.45), Cold Ethanolic (0.46), Hot Ethanolic (0.47) mouthwash groups.CONCLUSION:
Propolis was found to be as efficient as Chlorhexidine in reducing plaque, gingivitis and dental caries pathogens. CLINICAL RELEVANCE Common microorganisms implicated in oral disease are S. mutans and L. acidophilus. There is great paucity of information on antimicrobial activity of propolis, against these microorganisms. Hence, the present study has been taken up to assess the effects of propolis on these oral pathogens.The effects of propolis on oral health have been proved which is obviously a new finding of significance.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Propolis
/
Dental Caries
/
Dental Plaque
/
Gingivitis
/
Anti-Infective Agents, Local
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
Clin Oral Investig
Journal subject:
ODONTOLOGIA
Year:
2021
Type:
Article
Affiliation country:
India