Medication adherence is influenced by resilience in patients with systemic lupus erythematosus.
Lupus
; 30(7): 1051-1057, 2021 Jun.
Article
in En
| MEDLINE
| ID: mdl-33794703
ABSTRACT
OBJECTIVE:
Evidence on the relationship between resilience and medication adherence in systemic lupus erythematosus (SLE) patients is lacking. We aimed to examine the impact of resilience on medication adherence in SLE patients.METHOD:
In a cross-sectional analysis SLE outpatients were assessed for resilience (Connor-Davison Resilience Scale, CD-RISC), depressive symptoms (CES-D) and medication adherence (Compliance Questionnaire for Rheumatology [CQR]). The disease activity index (mexSLEDAI) and damage (SLICC Damage Index) were administered. Factors independently associated with adherence were identified using multivariate logistic regression.RESULTS:
Of the 157 patients, 152 (96.8%) were female with a median age of 45.9 (IQR 39.0-55.5) years and disease duration of 14 (IQR 10.0-19.0) years. Medication adherence (CQR ≥80%) and depressive symptoms were found in 74.5% and 43.9% of patients, respectively. Adherent patients had a lower CES-D score and a higher CD-RISC score. In the multivariate analysis adjusting for demographic and clinical confounders, resilience and older age protected against non-adherence (OR 0.96, [95% CI 0.94-0.99] and OR 0.96 [95% CI 0.93-0.98], respectively).CONCLUSION:
In SLE patients, resilience and older age, which possibly associated with better medication adherence, may protect against non-adherence.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Depression
/
Medication Adherence
/
Lupus Erythematosus, Systemic
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Mexico
Language:
En
Journal:
Lupus
Journal subject:
REUMATOLOGIA
Year:
2021
Type:
Article