Clinical Perspective on Proteomic and Glycomic Biomarkers for Diagnosis, Prognosis, and Prediction of Pancreatic Cancer.

Hanna-Sawires, Randa G; Schiphuis, Jorinde H; Wuhrer, Manfred; Vasen, Hans F A; van Leerdam, Monique E; Bonsing, Bert A; Mesker, Wilma E; van der Burgt, Yuri E M; Tollenaar, Rob A E M

Hanna-Sawires, Randa G; Schiphuis, Jorinde H; Wuhrer, Manfred; Vasen, Hans F A; van Leerdam, Monique E; Bonsing, Bert A; Mesker, Wilma E; van der Burgt, Yuri E M; Tollenaar, Rob A E M.

Affiliation

Hanna-Sawires RG; Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Schiphuis JH; Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Wuhrer M; Center of Proteomics and Metabolomics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Vasen HFA; Department of Gastroenterology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
van Leerdam ME; Department of Gastroenterology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Bonsing BA; Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Mesker WE; Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
van der Burgt YEM; Center of Proteomics and Metabolomics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

Int J Mol Sci ; 22(5)2021 Mar 06.

Article in En | MEDLINE | ID: mdl-33800786

Subject(s)

Biomarkers, Tumor/analysis; Carcinoma, Pancreatic Ductal/diagnosis; Glycomics/methods; Glycoproteins/analysis; Mass Spectrometry/methods; Neoplasm Proteins/analysis; Pancreatic Neoplasms/diagnosis; Proteomics/methods; Body Fluids/chemistry; Carcinoma, Pancreatic Ductal/chemistry; Carcinoma, Pancreatic Ductal/genetics; Carcinoma, Pancreatic Ductal/mortality; Clinical Decision-Making; Diagnosis, Differential; Early Detection of Cancer; Humans; Neoplastic Syndromes, Hereditary/diagnosis; Neoplastic Syndromes, Hereditary/epidemiology; Neoplastic Syndromes, Hereditary/genetics; Pancreatic Neoplasms/chemistry; Pancreatic Neoplasms/genetics; Pancreatic Neoplasms/mortality; Pancreatitis, Chronic/diagnosis; Precancerous Conditions/diagnosis; Precision Medicine; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors

Key words

CA 19-9; biomarker; early detection; glycomics; glycosylation; mass spectrometry; pancreatic cancer; prediction; prognosis; proteomics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Mass Spectrometry / Glycoproteins / Biomarkers, Tumor / Carcinoma, Pancreatic Ductal / Proteomics / Glycomics / Neoplasm Proteins Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies / Systematic_reviews Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: Netherlands

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