Insight into Gentisic Acid Antidiabetic Potential Using In Vitro and In Silico Approaches.

Mechchate, Hamza; Es-Safi, Imane; Mohamed Al Kamaly, Omkulthom; Bousta, Dalila

Mechchate, Hamza; Es-Safi, Imane; Mohamed Al Kamaly, Omkulthom; Bousta, Dalila.

Affiliation

Mechchate H; Laboratory of Biotechnology, Environment, Agrifood, and Health, Department of Biology, University of Sidi Mohamed Ben Abdellah, FSDM-Fez 30050, Morocco.
Es-Safi I; Laboratory of Biotechnology, Environment, Agrifood, and Health, Department of Biology, University of Sidi Mohamed Ben Abdellah, FSDM-Fez 30050, Morocco.
Mohamed Al Kamaly O; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
Bousta D; Laboratory of Biotechnology, Environment, Agrifood, and Health, Department of Biology, University of Sidi Mohamed Ben Abdellah, FSDM-Fez 30050, Morocco.

Molecules ; 26(7)2021 Mar 30.

Article in En | MEDLINE | ID: mdl-33808152

Subject(s)

Fruit/chemistry; Gentisates/metabolism; Glycoside Hydrolase Inhibitors/metabolism; Hypoglycemic Agents/metabolism; alpha-Amylases; alpha-Glucosidases/metabolism; Humans; Molecular Docking Simulation; Protein Binding; alpha-Amylases/antagonists & inhibitors; alpha-Amylases/metabolism

Key words

AldR; DPP4; FFAR1; GP; PPAR-Î³; PTP1B; gentisic acid; in silico; in vitro; molecular docking; α-amylase; α-glucosidase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alpha-Amylases / Alpha-Glucosidases / Glycoside Hydrolase Inhibitors / Fruit / Gentisates / Hypoglycemic Agents Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Type: Article Affiliation country: Morocco

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