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Copanlisib plus rituximab versus placebo plus rituximab in patients with relapsed indolent non-Hodgkin lymphoma (CHRONOS-3): a double-blind, randomised, placebo-controlled, phase 3 trial.
Matasar, Matthew J; Capra, Marcelo; Özcan, Muhit; Lv, Fangfang; Li, Wei; Yañez, Eduardo; Sapunarova, Katya; Lin, Tongyu; Jin, Jie; Jurczak, Wojciech; Hamed, Aryan; Wang, Ming-Chung; Baker, Ross; Bondarenko, Igor; Zhang, Qingyuan; Feng, Jifeng; Geissler, Klaus; Lazaroiu, Mihaela; Saydam, Guray; Szomor, Árpád; Bouabdallah, Krimo; Galiulin, Rinat; Uchida, Toshiki; Soler, Lidia Mongay; Cao, Anjun; Hiemeyer, Florian; Mehra, Aruna; Childs, Barrett H; Shi, Yuankai; Zinzani, Pier Luigi.
Affiliation
  • Matasar MJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: matasarm@mskcc.org.
  • Capra M; Centro de Hematologia e Oncologia, Hospital Mãe de Deus, Porto Alegre, Brazil.
  • Özcan M; Ankara University School of Medicine, Ankara, Turkey.
  • Lv F; Fudan University Shanghai Cancer Center, Shanghai, China.
  • Li W; The First Hospital of Jilin University, Changchun, China.
  • Yañez E; Oncology-Hematology Unit, Department of Internal Medicine, School of Medicine, University of La Frontera, Temuco, Chile.
  • Sapunarova K; Medical University, Plovdiv, Bulgaria.
  • Lin T; Sun Yat-sen University Cancer Center, Guangzhou, China.
  • Jin J; The First Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China.
  • Jurczak W; Maria Sklodowska-Curie National Research Institute of Oncology, Krakow, Poland.
  • Hamed A; Petz Aladár Megyei Oktató Kórház, Gyor, Hungary.
  • Wang MC; Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
  • Baker R; Hollywood Private Hospital, Nedlands, WA, Australia.
  • Bondarenko I; Chemotherapy Department, City Dnipropetrovsk Multi-field Clinical Hospital, 4 DSMA, Dnipro, Ukraine.
  • Zhang Q; Harbin Medical University Cancer Hospital, Harbin, China.
  • Feng J; Jiangsu Cancer Hospital, Nanjing, China.
  • Geissler K; Sigmund Freud University, Vienna, Austria.
  • Lazaroiu M; SC Policlinica de Diagnostic Rapid SA, Brasov, Romania.
  • Saydam G; Ege Üniversitesi Tip Fakültesi, Izmir, Turkey.
  • Szomor Á; Pécsi Tudományegyetem Klinikai Központ, Pécs, Hungary.
  • Bouabdallah K; Hematology and Cellular Therapy Department, University Hospital of Bordeaux, Bordeaux, France.
  • Galiulin R; Department of Chemotherapy for Children and Adults, Clinical Oncological Dispensary of Omsk Region, Omsk, Russian Federation.
  • Uchida T; Hematology and Oncology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan.
  • Soler LM; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Cao A; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Hiemeyer F; Pharmaceuticals Division, Bayer, Berlin, Germany.
  • Mehra A; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Childs BH; Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Shi Y; Department of Medical Oncology, National Cancer Center-National Clinical Research Center for Cancer-Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: syuankai@cicams.ac.cn.
  • Zinzani PL; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", and Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy.
Lancet Oncol ; 22(5): 678-689, 2021 05.
Article in En | MEDLINE | ID: mdl-33848462
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Quinazolines / Lymphoma, Non-Hodgkin / Antineoplastic Combined Chemotherapy Protocols / Rituximab / Phosphoinositide-3 Kinase Inhibitors Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2021 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Quinazolines / Lymphoma, Non-Hodgkin / Antineoplastic Combined Chemotherapy Protocols / Rituximab / Phosphoinositide-3 Kinase Inhibitors Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2021 Type: Article