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The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways.
Laporte, Manon; Raeymaekers, Valerie; Van Berwaer, Ria; Vandeput, Julie; Marchand-Casas, Isabel; Thibaut, Hendrik-Jan; Van Looveren, Dominique; Martens, Katleen; Hoffmann, Markus; Maes, Piet; Pöhlmann, Stefan; Naesens, Lieve; Stevaert, Annelies.
Affiliation
  • Laporte M; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Raeymaekers V; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Van Berwaer R; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Vandeput J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Marchand-Casas I; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Thibaut HJ; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Van Looveren D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Translational Platform Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Martens K; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Hoffmann M; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Translational Platform Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Maes P; KU Leuven, Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Unit, Leuven, Belgium.
  • Pöhlmann S; German Primate Center-Leibniz Institute for Primate Research, Infection Biology Unit, Göttingen, Germany.
  • Naesens L; University Göttingen, Faculty of Biology and Psychology, Göttingen, Germany.
  • Stevaert A; KU Leuven, Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, Leuven, Belgium.
PLoS Pathog ; 17(4): e1009500, 2021 04.
Article in En | MEDLINE | ID: mdl-33886690
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory System / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: PLoS Pathog Year: 2021 Type: Article Affiliation country: Belgium
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory System / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: PLoS Pathog Year: 2021 Type: Article Affiliation country: Belgium