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Trametinib therapy for children with neurofibromatosis type 1 and life-threatening plexiform neurofibroma or treatment-refractory low-grade glioma.
Ronsley, Rebecca; Hounjet, Celine D; Cheng, Sylvia; Rassekh, Shahrad Rod; Duncan, Walter J; Dunham, Christopher; Gardiner, Jane; Ghag, Arvindera; Ludemann, Jeffrey P; Wensley, David; Rehmus, Wingfield; Sargent, Michael A; Hukin, Juliette.
Affiliation
  • Ronsley R; Division of Hematology, Oncology & BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Hounjet CD; Faculty of Medicine, University of British Columbia, Vancouver, Canada.
  • Cheng S; Division of Hematology, Oncology & BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Rassekh SR; Division of Hematology, Oncology & BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Duncan WJ; Division of Pediatric Cardiology, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Dunham C; Division of Anatomic Pathology, Department of Pathology, University of British Columbia, Vancouver, Canada.
  • Gardiner J; Division of Pediatric Ophthalmology, Department of Surgery, University of British Columbia, Vancouver, Canada.
  • Ghag A; Division of Pediatric Orthopedic Surgery, Department of Surgery, University of British Columbia, Vancouver, Canada.
  • Ludemann JP; Division of Pediatric Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, Canada.
  • Wensley D; Division of Pediatric Respiratory Medicine, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Rehmus W; Division of Dermatology, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Sargent MA; Division of Pediatric Neuro-Radiology, Department of Radiology, University of British Columbia, Vancouver, Canada.
  • Hukin J; Division of Hematology, Oncology & BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
Cancer Med ; 10(11): 3556-3564, 2021 06.
Article in En | MEDLINE | ID: mdl-33939292
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Pyrimidinones / Brain Neoplasms / Neurofibromatosis 1 / Neurofibroma, Plexiform / Glioma / Antineoplastic Agents Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: America do norte Language: En Journal: Cancer Med Year: 2021 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Pyrimidinones / Brain Neoplasms / Neurofibromatosis 1 / Neurofibroma, Plexiform / Glioma / Antineoplastic Agents Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: America do norte Language: En Journal: Cancer Med Year: 2021 Type: Article Affiliation country: Canada