ß-Glucan-stimulated neutrophil secretion of IL-1&#945; is independent of GSDMD and mediated through extracellular vesicles.

Ratitong, Bridget; Marshall, Michaela; Pearlman, Eric

ß-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles.

Ratitong, Bridget; Marshall, Michaela; Pearlman, Eric.

Affiliation

Ratitong B; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA; Institute for Immunology, University of California, Irvine, Irvine, CA, USA. Electronic address: bratiton@uci.edu.
Marshall M; Department of Ophthalmology, University of California, Irvine, Irvine, CA, USA.
Pearlman E; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA; Department of Ophthalmology, University of California, Irvine, Irvine, CA, USA; Institute for Immunology, University of California, Irvine, Irvine, CA, USA. Electronic address: eric.pearlman@uci.edu.

Cell Rep ; 35(7): 109139, 2021 05 18.

Article in En | MEDLINE | ID: mdl-34010648

Subject(s)

Extracellular Vesicles/metabolism; Interleukin-1alpha/metabolism; Neutrophils/metabolism; Phosphate-Binding Proteins/metabolism; Pore Forming Cytotoxic Proteins/metabolism; beta-Glucans/metabolism; Animals; Female; Humans; Male; Mice

Key words

Dendritic cells; Exosomes; Extracellular vesicles; Gasdermin D; IL-1α; IL-1ß; Macrophages; Neutrophils; Pyroptosis; ß-glucan

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphate-Binding Proteins / Beta-Glucans / Interleukin-1alpha / Pore Forming Cytotoxic Proteins / Extracellular Vesicles / Neutrophils Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cell Rep Year: 2021 Type: Article

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