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Combined histopathological risk score using TP53 protein expression, CD8+ T cell density and intratumoral budding is an independent predictor of neoadjuvant therapy response in rectal adenocarcinoma.
Chen, Wei; Farchoukh, Lama; Seigh, Lindsey; Hartman, Douglas J; Pai, Reetesh K.
Affiliation
  • Chen W; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Farchoukh L; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Seigh L; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Hartman DJ; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Pai RK; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Histopathology ; 79(5): 826-835, 2021 Nov.
Article in En | MEDLINE | ID: mdl-34121230
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / CD8-Positive T-Lymphocytes / Neoadjuvant Therapy Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Histopathology Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / CD8-Positive T-Lymphocytes / Neoadjuvant Therapy Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Histopathology Year: 2021 Type: Article Affiliation country: United States