The road to generating transplantable organs: from blastocyst complementation to interspecies chimeras.

Zheng, Canbin; Ballard, Emily B; Wu, Jun

Zheng, Canbin; Ballard, Emily B; Wu, Jun.

Affiliation

Zheng C; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ballard EB; Department of Microsurgery, Orthopaedic Trauma and Hand Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Wu J; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Development ; 148(12)2021 06 15.

Article in En | MEDLINE | ID: mdl-34132325

Subject(s)

Blastocyst/cytology; Chimera; Organogenesis; Transplants; Animals; Apoptosis; Blastocyst/metabolism; Cell Differentiation; Histocompatibility; Humans; Livestock; Organ Specificity; Pluripotent Stem Cells/cytology; Pluripotent Stem Cells/metabolism; Transplantation, Heterologous

Key words

Blastocyst complementation; Chimera competency; Interspecies chimera; Interspecies organogenesis; Pluripotent stem cell; Xenogeneic barriers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blastocyst / Chimera / Transplants / Organogenesis Limits: Animals / Humans Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2021 Type: Article Affiliation country: United States

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