Noninvasive Detection of Hepatocellular Carcinoma with Circulating Tumor DNA Features and &#945;-Fetoprotein.

Meng, Zuowei; Ren, Qingqi; Zhong, Guolin; Li, Shiyong; Chen, Yan; Wu, Wei; Feng, Yumin; Mao, Mao; Zhang, Feng; Long, Guanghui

Noninvasive Detection of Hepatocellular Carcinoma with Circulating Tumor DNA Features and α-Fetoprotein.

Meng, Zuowei; Ren, Qingqi; Zhong, Guolin; Li, Shiyong; Chen, Yan; Wu, Wei; Feng, Yumin; Mao, Mao; Zhang, Feng; Long, Guanghui.

Affiliation

Meng Z; Peking University Shenzhen Hospital, Shenzhen, China.
Ren Q; Peking University Shenzhen Hospital, Shenzhen, China.
Zhong G; Research & Development, SeekIn Inc., Shenzhen, China.
Li S; Research & Development, SeekIn Inc., Shenzhen, China.
Chen Y; Research & Development, SeekIn Inc., Shenzhen, China.
Wu W; Research & Development, SeekIn Inc., Shenzhen, China.
Feng Y; Research & Development, SeekIn Inc., Shenzhen, China.
Mao M; Research & Development, SeekIn Inc., Shenzhen, China; Yonsei Song-Dang Institute for Cancer Research, Yonsei University, Seoul, Republic of Korea. Electronic address: maomao@yuhs.ac.
Zhang F; Research & Development, SeekIn Inc., Shenzhen, China. Electronic address: zhangfeng@seekin.onaliyun.com.
Long G; Peking University Shenzhen Hospital, Shenzhen, China.

J Mol Diagn ; 23(9): 1174-1184, 2021 09.

Article in En | MEDLINE | ID: mdl-34182124

Subject(s)

Carcinoma, Hepatocellular/blood; Carcinoma, Hepatocellular/diagnosis; Circulating Tumor DNA/blood; Early Detection of Cancer/methods; Liver Neoplasms/blood; Liver Neoplasms/diagnosis; alpha-Fetoproteins/analysis; Adult; Aged; Biomarkers, Tumor/blood; Case-Control Studies; Circulating Tumor DNA/genetics; Circulating Tumor DNA/isolation & purification; Cost-Benefit Analysis; DNA Copy Number Variations; Data Accuracy; Early Detection of Cancer/economics; Female; Humans; Male; Middle Aged; Sensitivity and Specificity

Key words

AFP; CNA; HCC; early detection; fragment size

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alpha-Fetoproteins / Carcinoma, Hepatocellular / Early Detection of Cancer / Circulating Tumor DNA / Liver Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Mol Diagn Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: China

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