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Indications for and contraindications of immune checkpoint inhibitors in cancer patients with COVID-19 vaccination.
Luo, Bangyu; Li, Jixi; Hou, Xianhua; Yang, Qiao; Zhou, Yi; Ye, Jun; Wu, Xiaocheng; Feng, Yimei; Hu, Tianyu; Xu, Zhi; He, Ying; Sun, Jianguo.
Affiliation
  • Luo B; Cancer Institute, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Li J; Cancer Institute, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Hou X; Department of Neurology, First Affiliated Hospital, Army Medical University, Chongqing, China.
  • Yang Q; Department of Ultrasound, 941 Hospital of The Chinese People's Liberation Army, Xining, China.
  • Zhou Y; Cancer Institute, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Ye J; Department of Gastroenterology, First Affiliated Hospital, Army Medical University, Chongqing, China.
  • Wu X; Department of Emergency, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Feng Y; Department of Hematology, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Hu T; Department of Nosocomial Infection Control, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Xu Z; Institute of Respiratory Diseases, Key Laboratory of Respiratory Diseases Research, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • He Y; Department of Neurology, Second Affiliated Hospital, Army Medical University, Chongqing, China.
  • Sun J; Cancer Institute, Second Affiliated Hospital, Army Medical University, Chongqing, China.
Future Oncol ; 17(26): 3477-3484, 2021 Sep.
Article in En | MEDLINE | ID: mdl-34189948
Lay abstract The COVID-19 pandemic has lasted over 1 year. Vaccination is a promising strategy for preventing COVID-19. Cancer patients are prone to infection with COVID-19, and these patients have high mortality. Immune checkpoint inhibitors (ICIs) are a novel anticancer strategy. Whether COVID-19 vaccination and ICI treatment impact each other in cancer patients remains unknown. This review explores both sides of the relationship between ICI treatment and COVID-19 vaccination and suggests good efficacy and safety of ICI treatment after COVID-19 vaccination as well as little impact on the virus protection and toxicity associated with COVID-19 vaccination during ICI treatment.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immune Checkpoint Inhibitors / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Future Oncol Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immune Checkpoint Inhibitors / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Future Oncol Year: 2021 Type: Article Affiliation country: China