Betaine downregulates microRNA 34a expression via a p53-dependent manner in cisplatin-induced nephrotoxicity in rats.

Hussein, Rasha M; Al-Dalain, Saed M

Hussein, Rasha M; Al-Dalain, Saed M.

Affiliation

Hussein RM; Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Mutah University, Al-Karak, Jordan.
Al-Dalain SM; Department of Biochemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

J Biochem Mol Toxicol ; 35(9): e22856, 2021 Sep.

Article in En | MEDLINE | ID: mdl-34318554

Subject(s)

Betaine/pharmacology; Cisplatin/adverse effects; Down-Regulation/drug effects; Kidney Diseases; MicroRNAs/biosynthesis; Tumor Suppressor Protein p53/biosynthesis; Animals; Cisplatin/pharmacology; Kidney Diseases/chemically induced; Kidney Diseases/metabolism; Male; Rats; Rats, Wistar

Key words

apoptosis; betaine; cisplatin; inflammation; kidney; microRNA

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Betaine / Down-Regulation / Tumor Suppressor Protein p53 / Cisplatin / MicroRNAs / Kidney Diseases Limits: Animals Language: En Journal: J Biochem Mol Toxicol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Year: 2021 Type: Article Affiliation country: Jordan

Fulltext

XML

PubMed Links

Search on Google