Identification of structures for ion channel kinetic models.

Mangold, Kathryn E; Wang, Wei; Johnson, Eric K; Bhagavan, Druv; Moreno, Jonathan D; Nerbonne, Jeanne M; Silva, Jonathan R

Mangold, Kathryn E; Wang, Wei; Johnson, Eric K; Bhagavan, Druv; Moreno, Jonathan D; Nerbonne, Jeanne M; Silva, Jonathan R.

Affiliation

Mangold KE; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Wang W; Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis Missouri, United States of America.
Johnson EK; Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis Missouri, United States of America.
Bhagavan D; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Moreno JD; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Nerbonne JM; Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis Missouri, United States of America.
Silva JR; Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis Missouri, United States of America.

PLoS Comput Biol ; 17(8): e1008932, 2021 08.

Article in En | MEDLINE | ID: mdl-34398881

Subject(s)

Ion Channels/metabolism; Models, Cardiovascular; Myocardium/metabolism; Action Potentials; Animals; Biophysical Phenomena; Computational Biology; Computer Simulation; Databases, Factual; HEK293 Cells; Heart Atria/metabolism; Heart Ventricles/metabolism; Humans; Ion Channels/chemistry; Kinetics; Markov Chains; Mice; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated/chemistry; Potassium Channels, Voltage-Gated/metabolism; Voltage-Gated Sodium Channels/chemistry; Voltage-Gated Sodium Channels/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ion Channels / Models, Cardiovascular / Myocardium Type of study: Diagnostic_studies / Health_economic_evaluation / Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2021 Type: Article Affiliation country: United States

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