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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment.
Sun, Hua; Cao, Song; Mashl, R Jay; Mo, Chia-Kuei; Zaccaria, Simone; Wendl, Michael C; Davies, Sherri R; Bailey, Matthew H; Primeau, Tina M; Hoog, Jeremy; Mudd, Jacqueline L; Dean, Dennis A; Patidar, Rajesh; Chen, Li; Wyczalkowski, Matthew A; Jayasinghe, Reyka G; Rodrigues, Fernanda Martins; Terekhanova, Nadezhda V; Li, Yize; Lim, Kian-Huat; Wang-Gillam, Andrea; Van Tine, Brian A; Ma, Cynthia X; Aft, Rebecca; Fuh, Katherine C; Schwarz, Julie K; Zevallos, Jose P; Puram, Sidharth V; Dipersio, John F; Davis-Dusenbery, Brandi; Ellis, Matthew J; Lewis, Michael T; Davies, Michael A; Herlyn, Meenhard; Fang, Bingliang; Roth, Jack A; Welm, Alana L; Welm, Bryan E; Meric-Bernstam, Funda; Chen, Feng; Fields, Ryan C; Li, Shunqiang; Govindan, Ramaswamy; Doroshow, James H; Moscow, Jeffrey A; Evrard, Yvonne A; Chuang, Jeffrey H; Raphael, Benjamin J; Ding, Li.
Affiliation
  • Sun H; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Cao S; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Mashl RJ; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Mo CK; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Zaccaria S; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Wendl MC; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Davies SR; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Bailey MH; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Primeau TM; Department of Computer Science, Princeton University, Princeton, NJ, USA.
  • Hoog J; Computational Cancer Genomics Research Group and Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
  • Mudd JL; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Dean DA; Department of Mathematics, Washington University in St. Louis, St. Louis, MO, USA.
  • Patidar R; Department of Genetics, Washington University in St. Louis, St. Louis, MO, USA.
  • Chen L; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Wyczalkowski MA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Jayasinghe RG; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Rodrigues FM; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Terekhanova NV; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Li Y; Seven Bridges Genomics, Inc., Cambridge, Charlestown, MA, USA.
  • Lim KH; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Wang-Gillam A; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Van Tine BA; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Ma CX; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Aft R; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Fuh KC; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Schwarz JK; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Zevallos JP; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Puram SV; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Dipersio JF; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Davis-Dusenbery B; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
  • Ellis MJ; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Lewis MT; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Davies MA; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Herlyn M; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Fang B; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Roth JA; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Welm AL; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Welm BE; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Meric-Bernstam F; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Chen F; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Fields RC; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Li S; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Govindan R; Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, USA.
  • Doroshow JH; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Moscow JA; Department of Otolaryngology, Washington University St. Louis, St. Louis, MO, USA.
  • Evrard YA; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Chuang JH; Department of Otolaryngology, Washington University St. Louis, St. Louis, MO, USA.
  • Raphael BJ; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Ding L; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
Nat Commun ; 12(1): 5086, 2021 08 24.
Article in En | MEDLINE | ID: mdl-34429404
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xenograft Model Antitumor Assays / Heterografts / Neoplasms Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xenograft Model Antitumor Assays / Heterografts / Neoplasms Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States