Chemistry of Peptide-Oligonucleotide Conjugates: A Review.

Klabenkova, Kristina; Fokina, Alesya; Stetsenko, Dmitry

Klabenkova, Kristina; Fokina, Alesya; Stetsenko, Dmitry.

Affiliation

Klabenkova K; Faculty of Physics, Novosibirsk State University, 630090 Novosibirsk, Russia.
Fokina A; Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, 630090 Novosibirsk, Russia.
Stetsenko D; Faculty of Physics, Novosibirsk State University, 630090 Novosibirsk, Russia.

Molecules ; 26(17)2021 Sep 06.

Article in En | MEDLINE | ID: mdl-34500849

Subject(s)

Cell-Penetrating Peptides/chemistry; Delayed-Action Preparations/chemistry; Oligonucleotides/chemistry; Amino Acid Sequence; CRISPR-Cas Systems; Cell Membrane Permeability; Cell-Penetrating Peptides/metabolism; Click Chemistry; Drug Liberation; Humans; Nucleic Acids; Oligonucleotides/metabolism; RNA, Small Interfering/chemistry; Solid-Phase Synthesis Techniques

Key words

antisense oligonucleotide; cell-penetrating peptide; cellular uptake; click chemistry; drug delivery; locked nucleic acid (LNA); nucleic acid therapeutic; peptide nucleic acid (PNA); phosphordiamidate morpholino oligomer (PMO); small interfering RNA (siRNA)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Delayed-Action Preparations / Cell-Penetrating Peptides Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Type: Article Affiliation country: RUSSIA

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