The past, present, and future of enzyme-based therapies.

Hennigan, Jennifer N; Lynch, Michael D

Hennigan, Jennifer N; Lynch, Michael D.

Affiliation

Hennigan JN; Department of Chemistry, Duke University, Durham, NC, USA.
Lynch MD; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Electronic address: michael.lynch@duke.edu.

Drug Discov Today ; 27(1): 117-133, 2022 01.

Article in En | MEDLINE | ID: mdl-34537332

Subject(s)

Drug Discovery/methods; Enzyme Replacement Therapy; Enzyme Therapy; Enzymes; Drug Development/methods; Enzyme Replacement Therapy/methods; Enzyme Replacement Therapy/trends; Enzyme Therapy/methods; Enzyme Therapy/trends; Enzymes/classification; Enzymes/pharmacology; Humans

Key words

Biologic; Biotechnology; Clinical; Early investigational; Enzyme; Enzyme based therapy; History; Pre-clinical; Therapeutic enzymes; Therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzymes / Drug Discovery / Enzyme Replacement Therapy / Enzyme Therapy Type of study: Prognostic_studies Limits: Humans Language: En Journal: Drug Discov Today Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2022 Type: Article Affiliation country: United States

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