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1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors.
Cantini, Niccolo; Crocetti, Letizia; Guerrini, Gabriella; Vergelli, Claudia; Schepetkin, Igor A; Pallecchi, Marco; Bartolucci, Gianluca; Quinn, Mark T; Teodori, Elisabetta; Giovannoni, Maria Paola.
Affiliation
  • Cantini N; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Crocetti L; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy. Electronic address: letizia.crocetti@unifi.it.
  • Guerrini G; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Vergelli C; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Schepetkin IA; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
  • Pallecchi M; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Bartolucci G; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Quinn MT; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
  • Teodori E; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
  • Giovannoni MP; NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.
Bioorg Med Chem Lett ; 52: 128380, 2021 11 15.
Article in En | MEDLINE | ID: mdl-34563669
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Proteinase Inhibitors / Leukocyte Elastase Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Type: Article Affiliation country: Italy
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Proteinase Inhibitors / Leukocyte Elastase Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Type: Article Affiliation country: Italy