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Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment.
Tang Girdwood, Sonya; Dong, Min; Tang, Peter; Stoneman, Erin; Jones, Rhonda; Yunger, Toni; Ostermeier, Austin; Curry, Calise; Forton, Melissa; Hail, Traci; Mullaney, Randi; Lahni, Patrick; Punt, Nieko; Kaplan, Jennifer; Vinks, Alexander A.
Affiliation
  • Tang Girdwood S; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Dong M; Division of Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Tang P; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Stoneman E; Division of Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Jones R; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Yunger T; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Ostermeier A; Division of Pathology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Curry C; Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Forton M; Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Hail T; Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Mullaney R; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Lahni P; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Punt N; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Kaplan J; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Vinks AA; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Antimicrob Agents Chemother ; 66(1): e0142721, 2022 01 18.
Article in En | MEDLINE | ID: mdl-34633847
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ceftriaxone / Critical Illness Type of study: Health_economic_evaluation Limits: Adult / Child / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ceftriaxone / Critical Illness Type of study: Health_economic_evaluation Limits: Adult / Child / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2022 Type: Article Affiliation country: United States