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Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis.
Liao, Min; Dong, Qiongye; Chen, Ruiqing; Xu, Liqian; Jiang, Yuxuan; Guo, Zhenxing; Xiao, Min; He, Wei; Cao, Changcai; Hu, Ronghua; Sun, Wanling; Jiang, Hong; Wang, Jianwei.
Affiliation
  • Liao M; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
  • Dong Q; Key Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, 100190, Beijing, China.
  • Chen R; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
  • Xu L; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
  • Jiang Y; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
  • Guo Z; Department of Hematology/Oncology, First Hospital of Tsinghua University, 100016, Beijing, China.
  • Xiao M; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China.
  • He W; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China.
  • Cao C; Shandong Hongmai Biotechnology Co., Ltd. Room 1201, building B, Research Institute of Tianjin University, No. 51, Lutai Avenue, Zibo High tech Zone, 255000, Tianjin, China.
  • Hu R; Department of Hematology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
  • Sun W; Department of Hematology, Xuanwu Hospital, Capital Medical University, 100053, Beijing, China. wanlingsun@xwhosp.org.
  • Jiang H; Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, 310003, Hangzhou, China. jianghong961106@zju.edu.cn.
  • Wang J; School of Pharmaceutical Sciences, Tsinghua University, 100084, Beijing, China. jianweiwang@tsinghua.edu.cn.
Cell Death Discov ; 7(1): 297, 2021 Oct 18.
Article in En | MEDLINE | ID: mdl-34663800
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Death Discov Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Death Discov Year: 2021 Type: Article Affiliation country: China