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ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.
Bakr, Ali; Hey, Joschka; Sigismondo, Gianluca; Liu, Chun-Shan; Sadik, Ahmed; Goyal, Ashish; Cross, Alice; Iyer, Ramya Lakshmana; Müller, Patrick; Trauernicht, Max; Breuer, Kersten; Lutsik, Pavlo; Opitz, Christiane A; Krijgsveld, Jeroen; Weichenhan, Dieter; Plass, Christoph; Popanda, Odilia; Schmezer, Peter.
Affiliation
  • Bakr A; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Hey J; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Sigismondo G; Heidelberg University, Faculty of Biosciences, 69120 Heidelberg, Germany.
  • Liu CS; Division of Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), INF581, 69120 Heidelberg, Germany.
  • Sadik A; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Goyal A; DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Cross A; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Iyer RL; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Müller P; Imperial College London, London, SW7 2AZ, UK.
  • Trauernicht M; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Breuer K; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Lutsik P; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Opitz CA; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Krijgsveld J; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), INF280, 69120 Heidelberg, Germany.
  • Weichenhan D; DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Plass C; Neurology Clinic and National Center for Tumor Diseases, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Popanda O; Division of Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), INF581, 69120 Heidelberg, Germany.
  • Schmezer P; Heidelberg University, Medical Faculty, INF672, 69120, Heidelberg, Germany.
Nucleic Acids Res ; 49(20): 11666-11689, 2021 11 18.
Article in En | MEDLINE | ID: mdl-34718742
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Inhibitor of Differentiation Proteins / Homologous Recombination / Neoplasm Proteins Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: Nucleic Acids Res Year: 2021 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Inhibitor of Differentiation Proteins / Homologous Recombination / Neoplasm Proteins Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: Nucleic Acids Res Year: 2021 Type: Article Affiliation country: Germany