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Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH: A Longitudinal Multicentre Study.
Wilke, Carlo; Reich, Selina; van Swieten, John C; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Masellis, Mario; Tartaglia, Maria C; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio; Santana, Isabel; Ducharme, Simon; Butler, Chris R; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Bocchetta, Martina; Todd, Emily; Kuhle, Jens; Barro, Christian; Rohrer, Jonathan D; Synofzik, Matthis.
Affiliation
  • Wilke C; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.
  • Reich S; Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • van Swieten JC; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.
  • Borroni B; Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Sanchez-Valle R; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands.
  • Moreno F; Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Laforce R; Alzheimer's disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain.
  • Graff C; Cognitive Disorders Unit, Department of Neurology, Donostia University Hospital, San Sebastian, Spain.
  • Galimberti D; Neuroscience Area, Biodonostia Health Research Institute, San Sebastian, Spain.
  • Rowe JB; Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Quebec City, Canada.
  • Masellis M; Center for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Bioclinicum, Karolinska Institute, Solna, Sweden.
  • Tartaglia MC; Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital, Solna, Sweden.
  • Finger E; Fondazione IRCCS Ospedale Policlinico, Milan, Italy.
  • Vandenberghe R; University of Milan, Centro Dino Ferrari, Milan, Italy.
  • de Mendonça A; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Tagliavini F; Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, Canada.
  • Santana I; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada.
  • Ducharme S; Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
  • Butler CR; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium.
  • Gerhard A; Neurology Service, University Hospitals Leuven, Leuven, Belgium.
  • Levin J; Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Danek A; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
  • Otto M; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
  • Frisoni G; University Hospital of Coimbra (HUC), Neurology Service, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Ghidoni R; Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Sorbi S; Department of Psychiatry, McGill University Health Centre, McGill University, Montreal, Québec, Canada.
  • Bocchetta M; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Québec, Canada.
  • Todd E; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK.
  • Kuhle J; Department of Brain Sciences, Imperial College London, London, UK.
  • Barro C; Division of Neuroscience and Experimental Psychology, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK.
  • Rohrer JD; Neurologische Klinik, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Synofzik M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Ann Neurol ; 91(1): 33-47, 2022 01.
Article in En | MEDLINE | ID: mdl-34743360
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Neurofilament Proteins / Frontotemporal Dementia Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Neurol Year: 2022 Type: Article Affiliation country: Germany
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Neurofilament Proteins / Frontotemporal Dementia Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Neurol Year: 2022 Type: Article Affiliation country: Germany