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Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology.
Tian, Yuan; Wang, Yi; Jablonski, Angela M; Hu, Yinghui; Sugam, Jonathan A; Koglin, Markus; Stachel, Shawn J; Zhou, Heather; Uslaner, Jason M; Parmentier-Batteur, Sophie.
Affiliation
  • Tian Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA. Electronic address: yuan.tian1@merck.com.
  • Wang Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Jablonski AM; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Hu Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Sugam JA; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Koglin M; Mass Spectrometry & Biophysics, MRL, Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Stachel SJ; Chemistry, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Zhou H; Genetics and Pharmacogenomics, MRL, Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Uslaner JM; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Parmentier-Batteur S; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
Neurobiol Dis ; 161: 105548, 2021 12.
Article in En | MEDLINE | ID: mdl-34752923
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Lobar Degeneration / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2021 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Lobar Degeneration / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2021 Type: Article