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Factors associated with antibiotic administration delay among preterm infants with late-onset bloodstream infection.
Baczynski, M; Kharrat, A; Zhu, F; Ye, X Y; Shah, P S; Weisz, D E; Jain, A.
Affiliation
  • Baczynski M; Department of Respiratory Therapy, Mount Sinai Hospital, Toronto, ON, Canada.
  • Kharrat A; Department of Paediatrics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
  • Zhu F; Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
  • Ye XY; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Shah PS; Department of Paediatrics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Weisz DE; Department of Paediatrics, University of Toronto, Toronto, ON, Canada; Department of Newborn and Developmental Paediatrics, Sunnybrook Health Science Center, Toronto, ON, Canada.
  • Jain A; Department of Paediatrics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; Department of Physiology, University of Toronto, Toronto, ON, Canada. Electr
J Hosp Infect ; 120: 31-35, 2022 Feb.
Article in En | MEDLINE | ID: mdl-34800611
ABSTRACT
Early antibiotic administration is an important modifiable factor in reducing mortality from late-onset bloodstream infections in preterm infants. In a cohort study including 142 infants with non-coagulase negative staphylococcus bloodstream infection at two tertiary neonatal intensive care units, we identified typical practice-related factors that may be targeted to prevent delays in antibiotic administration. Collection of cerebrospinal fluid or urine sample before administering antibiotics, a longer time taken to site a peripheral intravenous catheter among those without pre-existing access, and a longer time taken to administer fluid boluses were associated with a longer than median time to antibiotic administration.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Infant, Premature / Sepsis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Infant / Newborn Language: En Journal: J Hosp Infect Year: 2022 Type: Article Affiliation country: Canada

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Infant, Premature / Sepsis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Infant / Newborn Language: En Journal: J Hosp Infect Year: 2022 Type: Article Affiliation country: Canada