Perinuclear positioning of endosomes can affect PS-ASO activities.

Liang, Xue-Hai; Nichols, Joshua G; Tejera, Dario; Crooke, Stanley T

Liang, Xue-Hai; Nichols, Joshua G; Tejera, Dario; Crooke, Stanley T.

Affiliation

Liang XH; Core Antisense Research, Ionis Pharmaceuticals, Inc., Carlsbad, CA 92010, USA.
Nichols JG; Core Antisense Research, Ionis Pharmaceuticals, Inc., Carlsbad, CA 92010, USA.
Tejera D; Neurology, Ionis Pharmaceuticals, Inc., Carlsbad, CA 92010, USA.
Crooke ST; Core Antisense Research, Ionis Pharmaceuticals, Inc., Carlsbad, CA 92010, USA.

Nucleic Acids Res ; 49(22): 12970-12985, 2021 12 16.

Article in En | MEDLINE | ID: mdl-34878127

Subject(s)

Cell Nucleus/metabolism; Endosomes/metabolism; Oligonucleotides, Antisense/metabolism; Thionucleotides/metabolism; Animals; Biological Transport; Cell Line, Tumor; Cells, Cultured; Dyneins/metabolism; Endoplasmic Reticulum/metabolism; HeLa Cells; Humans; Mice; Microscopy, Confocal; Microtubules/metabolism; Motion; Neoplasm Proteins/metabolism; Oligonucleotides, Antisense/genetics; Thionucleotides/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Thionucleotides / Cell Nucleus / Oligonucleotides, Antisense Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2021 Type: Article Affiliation country: United States

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