The impact of prehistoric human dispersals on the presence of tobacco-related oral cancer in Northeast India.

Kundu, Sharbadeb; Dhar, Bishal; Das, Raima; Laskar, Shaheen; Singh, Seram Anil; Kapfo, Wetetsho; Paul, Rajesh; Ramshankar, Vijayalakshmi; Choudhury, Yashmin; Ghosh, Sankar Kumar

Kundu, Sharbadeb; Dhar, Bishal; Das, Raima; Laskar, Shaheen; Singh, Seram Anil; Kapfo, Wetetsho; Paul, Rajesh; Ramshankar, Vijayalakshmi; Choudhury, Yashmin; Ghosh, Sankar Kumar.

Affiliation

Kundu S; Genome Science, School of Interdisciplinary Studies, University of Kalyani, Nadia 741235, West Bengal, India; Department of Biotechnology, Assam University, Silchar 788011, Assam, India.
Dhar B; S. N. Bose Innovation Centre, University of Kalyani, Nadia 741235, West Bengal, India.
Das R; Department of Biotechnology, Assam University, Silchar 788011, Assam, India.
Laskar S; Department of Biotechnology, Assam University, Silchar 788011, Assam, India.
Singh SA; Institute of Bioresources and Sustainable Development, Takyelpat, Imphal 795001, Manipur, India.
Kapfo W; Healthcare Laboratory and Research Centre, Naga Hospital Authority, Kohima 797001, Nagaland, India.
Paul R; Department of Animal Genetics and Breeding, College of Veterinary Science and Animal Husbandry, Tripura 799008, India.
Ramshankar V; Department of Preventive Oncology (Research), Cancer Institute (W.I.A.), Chennai 600020, Tamil Nadu, India.
Choudhury Y; Department of Biotechnology, Assam University, Silchar 788011, Assam, India.
Ghosh SK; Department of Biotechnology, Assam University, Silchar 788011, Assam, India. Electronic address: drsankarghosh@gmail.com.

Gene ; 813: 146098, 2022 Mar 01.

Article in En | MEDLINE | ID: mdl-34952175

Subject(s)

Mouth Neoplasms/epidemiology; Tobacco Use/epidemiology; Adult; Asian People/genetics; Case-Control Studies; DNA, Mitochondrial/genetics; Ethnicity/genetics; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genetics, Population/methods; Haplotypes; Human Migration; Humans; India/epidemiology; Male; Middle Aged; Mouth Neoplasms/blood; Mouth Neoplasms/etiology; Mouth Neoplasms/genetics; Phylogeny; Tobacco Smoking; Tobacco Use/blood; Tobacco Use/genetics; Young Adult

Key words

AMOVA; Anatomically modern human dispersal; Ancestry-specific allele frequency; Disease-associated admixture component; Global admixture analysis; Migration analysis; Mitochondrial macro-haplogroup diversity; Multidimensional scaling; Northeast India; Oral cancer susceptibility autosomal loci; Prehistoric migration route; Prolonged tobacco-chewers; Tobacco-related oral cancer; mtDNA-based marker

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mouth Neoplasms / Tobacco Use Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Gene Year: 2022 Type: Article Affiliation country: India

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