Droplet Degeneration of Hippocampal and Cortical Neurons Signifies the Beginning of Neuritic Plaque Formation.

Streit, Wolfgang J; Rotter, Jonas; Winter, Karsten; Müller, Wolf; Khoshbouei, Habibeh; Bechmann, Ingo

Streit, Wolfgang J; Rotter, Jonas; Winter, Karsten; Müller, Wolf; Khoshbouei, Habibeh; Bechmann, Ingo.

Affiliation

Streit WJ; Department of Neuroscience, University of Florida College of Medicine, Gainesville, FL, USA.
Rotter J; Institute of Anatomy, Leipzig University, Leipzig, Germany.
Winter K; Institute of Anatomy, Leipzig University, Leipzig, Germany.
Müller W; Department of Neuropathology, Leipzig University, Leipzig, Germany.
Khoshbouei H; Department of Neuroscience, University of Florida College of Medicine, Gainesville, FL, USA.
Bechmann I; Institute of Anatomy, Leipzig University, Leipzig, Germany.

J Alzheimers Dis ; 85(4): 1701-1720, 2022.

Article in En | MEDLINE | ID: mdl-34958037

Subject(s)

Hippocampus/pathology; Microglia/pathology; Neurons/pathology; Plaque, Amyloid/pathology; Aged; Aged, 80 and over; Alzheimer Disease/pathology; Autopsy; Brain/pathology; Female; Humans; Immunohistochemistry; Male; Neocortex/pathology

Key words

Amyloid-ß protein; ferritin; ferroptosis; iron; late-onset Alzheimer's disease; microglia; neuron loss

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Plaque, Amyloid / Hippocampus / Neurons Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2022 Type: Article Affiliation country: United States

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