Separation and Enrichment of Alkaloids from Coptidis Rhizoma and Euodiae Fructus by Macroporous Resin and Evaluation of the Effect on Bile Reflux Gastritis Rats.

Li, Yan-Ying; Feng, Jin-Lei; Li, Zheng; Zang, Xin-Yu; Yang, Xiu-Wei

Li, Yan-Ying; Feng, Jin-Lei; Li, Zheng; Zang, Xin-Yu; Yang, Xiu-Wei.

Affiliation

Li YY; State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Peking University, Beijing 101191, China.
Feng JL; TCM R&D Center, Beijing Increase Pharm Co., Ltd., Beijing 102200, China.
Li Z; TCM R&D Center, Tianjin Increase Innovative Drug Co., Ltd., Tianjin 300382, China.
Zang XY; TCM R&D Center, Tianjin Increase Innovative Drug Co., Ltd., Tianjin 300382, China.
Yang XW; TCM R&D Center, Beijing Increase Pharm Co., Ltd., Beijing 102200, China.

Molecules ; 27(3)2022 Jan 22.

Article in En | MEDLINE | ID: mdl-35163988

Subject(s)

Alkaloids/isolation & purification; Alkaloids/pharmacology; Bile Reflux/drug therapy; Coptis/chemistry; Evodia/chemistry; Gastritis/drug therapy; Resins, Plant/chemistry; Alkaloids/chemistry; Animals; Bile Reflux/metabolism; Bile Reflux/pathology; Gastritis/metabolism; Gastritis/pathology; Rats; Rats, Sprague-Dawley

Key words

Coptidis Rhizoma; Euodiae Fructus; UHPLCDAD; UHPLCESIQTOF-MS; bile reflux gastritis; enrichment and purification; gastric pathology; macroporous resin; rats; total alkaloids

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resins, Plant / Bile Reflux / Coptis / Evodia / Alkaloids / Gastritis Type of study: Evaluation_studies / Guideline / Qualitative_research Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: China

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